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WIP deficiency severely affects human lymphocyte architecture during migration and synapse assembly.

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To the editor: The high motility of immune cells and their ability to establish cell-to-cell contacts depend on a tight regulation of actin cytoskeleton dynamics. Murine studies have identified the… Click to show full abstract

To the editor: The high motility of immune cells and their ability to establish cell-to-cell contacts depend on a tight regulation of actin cytoskeleton dynamics. Murine studies have identified the Wiskott-Aldrich syndrome protein (WASP)-interacting protein (WIP) as a key regulator of actin

Keywords: deficiency severely; wip deficiency; severely affects; lymphocyte architecture; human lymphocyte; affects human

Journal Title: Blood
Year Published: 2017

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