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In this issue of Blood, O’Brien and colleagues1 demonstrate impaired growth of circulating red-cell progenitor cells ex vivo from patients with Diamond-Blackfan anemia (DBA) with ribosomal protein (RP) or GATA1… Click to show full abstract
In this issue of Blood, O’Brien and colleagues1 demonstrate impaired growth of circulating red-cell progenitor cells ex vivo from patients with Diamond-Blackfan anemia (DBA) with ribosomal protein (RP) or GATA1 mutations. Distinct transcriptional profiles in erythroid cells from patients with RP and GATA1 mutations indicate potential mechanisms underlying dysregulation of translation.1
Keywords:
translation gata1;
lost translation;
gata1;
gata1 mutations;
mutations dba
Journal Title: Blood
Year Published: 2017
Link to full text (if available)
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Journal Title: Blood
Year Published: 2017
Link to full text (if available)
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recommendations!