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Singling out FLI1 in Paris-Trousseau syndrome.

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In this issue of Blood, using induced pluripotent stem cell (iPSC)–derived human megakaryocytes (iMegs), Vo et al find that the megakaryocyte/platelet defects observed in patients with Paris-Trousseau syndrome (PTS) are… Click to show full abstract

In this issue of Blood, using induced pluripotent stem cell (iPSC)–derived human megakaryocytes (iMegs), Vo et al find that the megakaryocyte/platelet defects observed in patients with Paris-Trousseau syndrome (PTS) are due solely to hemizygous deletion of the transcription factor (TF) FLI1.1

Keywords: fli1 paris; singling fli1; trousseau syndrome; paris trousseau

Journal Title: Blood
Year Published: 2017

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