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In this issue of Blood , Arezes and colleagues present new and exciting evidence that erythropoietin (EPO) suppresses bone morphogenetic protein (BMP)-mediated signaling in an erythroferrone (ERFE)-dependent mechanism and ERFE… Click to show full abstract
In this issue of Blood , Arezes and colleagues present new and exciting evidence that erythropoietin (EPO) suppresses bone morphogenetic protein (BMP)-mediated signaling in an erythroferrone (ERFE)-dependent mechanism and ERFE in turn interferes with the binding of a specific set of BMPs to their receptors. 1 These findings represent a breakthrough in the understanding of how EPO and ERFE function to decrease hepcidin expression.
Keywords:
receptor erfe;
sought receptor;
erfe;
long sought
Journal Title: Blood
Year Published: 2018
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Journal Title: Blood
Year Published: 2018
Link to full text (if available)
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recommendations!