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Cuplike nuclear morphology is highly associated with IKZF1 deletion in pediatric precursor B-cell ALL.

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TO THE EDITOR: Cuplike nuclei (CLN) (nuclei with prominent invagination) are recognized as a distinctive morphologic finding in the blasts of acute myeloid leukemia (AML).[1][1][⇓][2][⇓][3][⇓][4][⇓][5]-[6][6] They are seen in ∼20%… Click to show full abstract

TO THE EDITOR: Cuplike nuclei (CLN) (nuclei with prominent invagination) are recognized as a distinctive morphologic finding in the blasts of acute myeloid leukemia (AML).[1][1][⇓][2][⇓][3][⇓][4][⇓][5]-[6][6] They are seen in ∼20% of all AML cases[2][2],[4][4],[5][5] and are associated

Keywords: highly associated; associated ikzf1; cuplike nuclear; ikzf1 deletion; nuclear morphology; morphology highly

Journal Title: Blood
Year Published: 2019

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