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Introduction to a Review Series on molecular mechanisms of hematologic malignancies.

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To reach the goal of curing currently incurable hematologic malignancies, we need to go beyond focusing on single gene mutatons and gain deeper understanding of the consequences of genetic alterations… Click to show full abstract

To reach the goal of curing currently incurable hematologic malignancies, we need to go beyond focusing on single gene mutatons and gain deeper understanding of the consequences of genetic alterations on gene-regulatory pathways. Edited by John Crispino, these 5 cutting-edge reviews from leaders in the their fields not only summarize our current understanding of key pathways that contribute to myeloid malignancies, but also discuss new therapeutic avenues related to them. They provide a springboard for further groundbreaking basic and clinical advances in hematologic malignancies.

Keywords: review series; mechanisms hematologic; hematologic malignancies; series molecular; introduction review; molecular mechanisms

Journal Title: Blood
Year Published: 2021

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