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The antibody-drug conjugate loncastuximab tesirine for the treatment of diffuse large B-cell lymphoma

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In this Blood Spotlight, Calabretta and colleagues describe the mechanism of action of loncastuximab tesirine, an anti-CD19 antibody-drug conjugate. They discuss data from the first phase 1 and 2 trials… Click to show full abstract

In this Blood Spotlight, Calabretta and colleagues describe the mechanism of action of loncastuximab tesirine, an anti-CD19 antibody-drug conjugate. They discuss data from the first phase 1 and 2 trials of the drug in patients with relapsed or refractory diffuse large B-cell lymphoma contributing to its recent approval by the US Food and Drug Administration.

Keywords: loncastuximab tesirine; large cell; diffuse large; drug conjugate; drug; antibody drug

Journal Title: Blood
Year Published: 2022

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