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Key Points • Murine allogeneic anti-CD19 CAR T cells integrated before or early after PTCy for allo-HCT can clear leukemia without added toxicity.• Clinical translation of this approach would combine… Click to show full abstract
Key Points • Murine allogeneic anti-CD19 CAR T cells integrated before or early after PTCy for allo-HCT can clear leukemia without added toxicity.• Clinical translation of this approach would combine the activity of both CAR T cells and polyclonal alloreactive T cells to reduce relapse.
Keywords:
integrated early;
murine allogeneic;
allogeneic car;
car;
cells integrated;
car cells
Journal Title: Blood
Year Published: 2022
Link to full text (if available)
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Journal Title: Blood
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!