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Key Points • CD53 is upregulated in HSCs in response to various inflammatory and proliferative stressors.• CD53 promotes HSC return to quiescence via promotion of the DREAM complex activity and… Click to show full abstract
Key Points • CD53 is upregulated in HSCs in response to various inflammatory and proliferative stressors.• CD53 promotes HSC return to quiescence via promotion of the DREAM complex activity and downregulation of cycling-associated genes.
Keywords:
cd53;
quiescence;
dream complex;
via promotion;
promotion dream
Journal Title: Blood
Year Published: 2022
Link to full text (if available)
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Journal Title: Blood
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!