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Key Points • Proximity proteomics and siRNA subscreens in endothelial cells reveal proteins associated with regulated actomyosin expulsion of VWF.• PAK2 and septin hetero-oligomeric complexes are required for actomyosin ring… Click to show full abstract
Key Points • Proximity proteomics and siRNA subscreens in endothelial cells reveal proteins associated with regulated actomyosin expulsion of VWF.• PAK2 and septin hetero-oligomeric complexes are required for actomyosin ring function and effective VWF release.
Keywords:
proteomics identifies;
expulsion;
identifies septins;
proximity;
proximity proteomics;
septins pak2
Journal Title: Blood
Year Published: 2022
Link to full text (if available)
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Journal Title: Blood
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!