LAUSR

Abstract Objectives: To evaluate the diagnostic performance and prognostic value of a Chinese DIC Scoring System (CDSS). Methods: 1076 patients suspected of DIC were enrolled in 18 hospitals located across virtually the entire China. Scores of DIC were calculated on days 1-3 and 7, when DIC were diagnosed against the CDSS, the Japanese Ministry of Health and Welfare (JMHW) criteria, and the International Society on Thrombosis and Hemostasis (ISTH) criteria respectively. Illness severity and organ failure were assessed against the Acute Physiology and Chronic Health Evaluation (APACHE) II and the Sequential Organ Failure Assessment (SOFA) score. 28-day all-cause mortality was taken as a major prognostic sign. Results: If 28-day all-cause mortality was used as a standard for DIC diagnosis, compared with the ISTH and JMHW criteria, the CDSS had the highest sensitivity (CDSS, 81.19%; ISTH, 71.29%; JMHW 74.26%, p Conclusions: Compared with the ISTH and JMHW criteria, the CDSS has better diagnostic performance and prognostic value in DIC patients with different underlying diseases. Disclosures No relevant conflicts of interest to declare.