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An Integrated Safety Analysis of the Next Generation PI3Kδ Inhibitor Umbralisib (TGR-1202) in Patients with Relapsed/Refractory Lymphoid Malignancies

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Matthew S. Davids, MD1, Ian W. Flinn, MD, PhD2,3, Anthony R. Mato, MD4, Owen A. O'Connor, M.D., Ph.D.5, Danielle M. Brander, MD6, Matthew A. Lunning, DO7, Julie M. Vose, MD,… Click to show full abstract

Matthew S. Davids, MD1, Ian W. Flinn, MD, PhD2,3, Anthony R. Mato, MD4, Owen A. O'Connor, M.D., Ph.D.5, Danielle M. Brander, MD6, Matthew A. Lunning, DO7, Julie M. Vose, MD, MBA7, Loretta Nastoupil, MD8, Nathan Fowler, MD8, Christopher Flowers, MD, MS9, Jennifer R. Brown, MD, PhD1, Marshall T. Schreeder, MD10, Nilanjan Ghosh, MD, PhD11, Frederick Lansigan, MD12, Bruce D. Cheson, MD13, Paul M. Barr, MD14, John M. Pagel, MD, PhD15, Alexey Danilov, MD, PhD16, Javier Pinilla-Ibarz, MD, PhD17, Changchun Deng, MD, PhD5, John M. Burke, MD18,19, Tanya Siddiqi, MD20, Manish R Patel, MD2,21, Charles M. Farber, MD, PhD22, Parameswaran Venugopal, MD23, John G. Gribben, MD DSc FMedSci24, Pier Luigi Zinzani, MD, PhD25, Hari P Miskin, MSc26, Peter Sportelli, BS26, Michael S. Weiss26, and Susan M. O'Brien, MD27 1Dana-Farber Cancer Institute, Boston, MA; 2Sarah Cannon Research Institute, Nashville, TN; 3Tennessee Oncology PLLC, Nashville, TN; 4University of Pennsylvania, Philadelphia, PA; 5Center for Lymphoid Malignancies, Columbia University Medical Center, New York, NY; 6Duke University Medical Center, Durham, NC; 7University of Nebraska Medical Center, Omaha, NE; 8The University of Texas MD Anderson Cancer Center, Houston, TX; 9Winship Cancer Institute Bone Marrow & Stem Cell Transplantation, Atlanta, GA; 10Clearview Cancer Institute, Huntsville, AL; 11Levine Cancer Institute, Charlotte, NC; 12Dartmouth-Hitchcock Medical Center, Lebanon, NH; 13Georgetown University Medical Center, Washington, DC; 14Wilmot Cancer Institute, University of Rochester, Rochester, NY; 15Swedish Cancer Institute, Seattle, WA; 16Oregon Health & Science University, Portland, OR; 17H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL; 18Rocky Mountain Cancer Centers, Aurora, CO; 19US Oncology Research, The Woodlands, TX; 20City of Hope National Medical Center, Duarte, CA; 21Florida Cancer Specialists, Sarasota, FL; 22Summit Medical Group/MD Anderson Cancer Center, Morristown, NJ; 23Rush University Medical Center, Chicago, IL; 24Barts Hospital Cancer Institute, Queen Mary University of London, London, United Kingdom; 25Institute of Hematology "L. e A. Seràgnoli", University of Bologna, Bologna, Italy; 26TG Therapeutics, Inc., New York, NY; 27University of California Irvine, Chao Family Comprehensive Cancer Center, Orange, CA

Keywords: medical center; university; center; cancer; cancer institute

Journal Title: Blood
Year Published: 2017

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