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Proteasome inhibition activates multiple kinases in myeloma cells resulting in the phosphorylation of p53, HSP27, c-JUN, and HSF1.TG02 inhibits proteasome inhibitor (PI)-induced HSF1 pS326, representing a novel mechanism for a… Click to show full abstract
Proteasome inhibition activates multiple kinases in myeloma cells resulting in the phosphorylation of p53, HSP27, c-JUN, and HSF1.TG02 inhibits proteasome inhibitor (PI)-induced HSF1 pS326, representing a novel mechanism for a TG02 and PI combination.
Keywords:
inhibits proteasome;
proteasome inhibitor;
inhibitor induced;
tg02 inhibits;
induced hsf1;
phosphorylation
Journal Title: Blood advances
Year Published: 2017
Link to full text (if available)
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Journal Title: Blood advances
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!