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TREM-like transcript 1: a more sensitive marker of platelet activation than P-selectin in humans and mice.

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Key Points Platelet activation in vitro results in a more rapid and greater upregulation of TLT-1 surface expression compared with P-selectin. TLT-1 is more rapidly translocated to the surface of… Click to show full abstract

Key Points Platelet activation in vitro results in a more rapid and greater upregulation of TLT-1 surface expression compared with P-selectin. TLT-1 is more rapidly translocated to the surface of activated platelets than P-selectin during thrombus formation in vivo.

Keywords: sensitive marker; trem like; platelet activation; activation; like transcript; transcript sensitive

Journal Title: Blood advances
Year Published: 2018

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