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Bilateral retinal detachment after chimeric antigen receptor T-cell therapy.

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CAR T-cell targeting of leukemic infiltrates in the optic nerve and retina caused retinal detachment as a presentation of pseudoprogression. Treatment of this intraocular inflammation with intravitreal triamcinolone and orbital… Click to show full abstract

CAR T-cell targeting of leukemic infiltrates in the optic nerve and retina caused retinal detachment as a presentation of pseudoprogression. Treatment of this intraocular inflammation with intravitreal triamcinolone and orbital radiation led to marked improvement in visual acuity.

Keywords: bilateral retinal; detachment chimeric; retinal detachment; cell; chimeric antigen

Journal Title: Blood advances
Year Published: 2020

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