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Proteomic identification of proliferation and progression markers in human polycythemia vera stem and progenitor cells

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Key Points Proteomic profiling identifies downregulated CLU expression as potential driver of myeloid hyperproliferation in PV. We detect LGALS9 and SOCS2 protein expression in HSC/MPPs as possible markers for progressed… Click to show full abstract

Key Points Proteomic profiling identifies downregulated CLU expression as potential driver of myeloid hyperproliferation in PV. We detect LGALS9 and SOCS2 protein expression in HSC/MPPs as possible markers for progressed PV.

Keywords: progression markers; proliferation progression; proteomic identification; identification proliferation; markers human; human polycythemia

Journal Title: Blood Advances
Year Published: 2022

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