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Key Points FLT3-ITD and high PRDM16 expression induced methylation changes at STAT5 and AP-1 binding sites in pediatric AML. Hypomethylated regions in PRDM16-highly expressed AMLs were correlated with enhanced chromatin… Click to show full abstract
Key Points FLT3-ITD and high PRDM16 expression induced methylation changes at STAT5 and AP-1 binding sites in pediatric AML. Hypomethylated regions in PRDM16-highly expressed AMLs were correlated with enhanced chromatin accessibilities at multiple genomic regions.
Keywords:
methylation;
methylation analysis;
genome wide;
dna methylation;
analysis pediatric;
wide dna
Journal Title: Blood Advances
Year Published: 2022
Link to full text (if available)
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Journal Title: Blood Advances
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!