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Key Points A somatic UBA2 deletion preceded the well-established leukemia initiating event ETV6-RUNX1 fusion in monozygotic twins with BCP-ALL. A shared complex rearrangement created an ETV6-RUNX1 fusion and provided evidence… Click to show full abstract
Key Points A somatic UBA2 deletion preceded the well-established leukemia initiating event ETV6-RUNX1 fusion in monozygotic twins with BCP-ALL. A shared complex rearrangement created an ETV6-RUNX1 fusion and provided evidence of a common clonal in utero origin.
Keywords:
somatic uba2;
etv6 runx1;
variant preceded;
monozygotic twins;
uba2 variant
Journal Title: Blood Advances
Year Published: 2022
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Journal Title: Blood Advances
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!