LAUSR.org creates dashboard-style pages of related content for over 1.5 million academic articles. Sign Up to like articles & get recommendations!

IFNγ regulates NAD+ metabolism to promote the respiratory burst in human monocytes

Photo from wikipedia

Key Points IFNγ induces a highly oxidative metabolic phenotype with high rates of oxygen consumption by both mitochondria and NADPH oxidase. IFNγ induces a NAMPT-dependent, NAD+ salvage pathway that is… Click to show full abstract

Key Points IFNγ induces a highly oxidative metabolic phenotype with high rates of oxygen consumption by both mitochondria and NADPH oxidase. IFNγ induces a NAMPT-dependent, NAD+ salvage pathway that is required for complete induction of the respiratory burst in human monocytes.

Keywords: ifn regulates; human monocytes; respiratory burst; burst human

Journal Title: Blood Advances
Year Published: 2022

Link to full text (if available)


Share on Social Media:                               Sign Up to like & get
recommendations!

Related content

More Information              News              Social Media              Video              Recommended



                Click one of the above tabs to view related content.