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A single administration of hIL-7-hyFc induces long-lasting T-cell expansion with maintained effector functions

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Key Points • A single hIL-7-hyFc administration induced a sustained increase in the numbers of T cells, but not regulatory T cells, in healthy adults.• The effector functions of antigen-specific… Click to show full abstract

Key Points • A single hIL-7-hyFc administration induced a sustained increase in the numbers of T cells, but not regulatory T cells, in healthy adults.• The effector functions of antigen-specific CD8+ T cells were preserved after hIL-7-hyFc administration.

Keywords: administration; single administration; hil hyfc; effector functions; administration hil

Journal Title: Blood Advances
Year Published: 2022

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