Key Points • Platelet-targeted thrombolysis with SCE5-scuPA achieved favorable outcomes vs tenecteplase-tPA in 2 mouse models of ischemic stroke.• Thrombolytic strategies that harness activated platelets for drug targeting better suit… Click to show full abstract
Key Points • Platelet-targeted thrombolysis with SCE5-scuPA achieved favorable outcomes vs tenecteplase-tPA in 2 mouse models of ischemic stroke.• Thrombolytic strategies that harness activated platelets for drug targeting better suit the platelet-rich nature of stroke-causing thrombi.
               
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