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Key Points • A defined 3D in vitro model, under hypoxic condition, sustains long-term propagation of JMML cells with specific hallmarks.• In vitro low oxygen levels drive a metabolic switch… Click to show full abstract
Key Points • A defined 3D in vitro model, under hypoxic condition, sustains long-term propagation of JMML cells with specific hallmarks.• In vitro low oxygen levels drive a metabolic switch that redirect JMML cells toward self-renewal.
Keywords:
long term;
term proliferation;
proliferation immature;
jmml;
jmml cells
Journal Title: Blood Advances
Year Published: 2022
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Journal Title: Blood Advances
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!