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Identification of novel γ-globin inducers among all potential erythroid druggable targets

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Key Points New target genes for γ-globin induction identified among all current potential therapeutic agents in an erythroid-biased CRISPR screen. Top novel drug candidates and pathways for fetal hemoglobin induction… Click to show full abstract

Key Points New target genes for γ-globin induction identified among all current potential therapeutic agents in an erythroid-biased CRISPR screen. Top novel drug candidates and pathways for fetal hemoglobin induction examined and validated.

Keywords: potential erythroid; novel globin; globin inducers; inducers among; among potential; identification novel

Journal Title: Blood Advances
Year Published: 2022

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