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Key Points Selective advantage induced by clonal hematopoiesis-associated mutation in Dnmt3a is specific to the HSC compartment. Npm1 mutation alters chromatin accessibility in a cell-context and Dnmt3a mutation-dependent manner. Click to show full abstract
Key Points Selective advantage induced by clonal hematopoiesis-associated mutation in Dnmt3a is specific to the HSC compartment. Npm1 mutation alters chromatin accessibility in a cell-context and Dnmt3a mutation-dependent manner.
Keywords:
dependent cooperativity;
origin dependent;
dnmt3a;
cell origin;
clonal hematopoiesis
Journal Title: Blood Advances
Year Published: 2022
Link to full text (if available)
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Journal Title: Blood Advances
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!