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ICOS immunoPET enables visualization of activated T cells and early diagnosis of murine acute gastrointestinal GvHD

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Key Points ImmunoPET imaging of ICOS allows for in vivo visualization of T cells in the gastrointestinal tract in a murine model of acute GvHD. ICOS targeting with the immunoPET… Click to show full abstract

Key Points ImmunoPET imaging of ICOS allows for in vivo visualization of T cells in the gastrointestinal tract in a murine model of acute GvHD. ICOS targeting with the immunoPET tracer does not affect GvHD pathogenesis or the GvT effect.

Keywords: visualization; icos immunopet; icos; gvhd icos; murine

Journal Title: Blood Advances
Year Published: 2022

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