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Increasing tissue requirements in lymphoma trials may exclude patients with high-risk disease or worse prognosis

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Key Points • Patients who underwent core needle biopsy are more likely to have poor-risk disease features and inadequate tissue for molecular analyses.• Increasing tissue requirements of biomarker-driven trials may… Click to show full abstract

Key Points • Patients who underwent core needle biopsy are more likely to have poor-risk disease features and inadequate tissue for molecular analyses.• Increasing tissue requirements of biomarker-driven trials may exclude patients with high-risk DLBCL who need novel agents.

Keywords: increasing tissue; trials may; risk; risk disease; tissue requirements; tissue

Journal Title: Blood Advances
Year Published: 2022

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