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The VWF binding aptamer rondoraptivon pegol increases platelet counts and VWF/FVIII in type 2B von Willebrand disease

Key Points The aptamer rondoraptivon pegol improved VWF/FVIII levels, multimer patterns, and thrombocytopenia in type 2B von Willebrand disease. Once weekly subcutaneous injections of rondoraptivon pegol may in the future… Click to show full abstract

Key Points The aptamer rondoraptivon pegol improved VWF/FVIII levels, multimer patterns, and thrombocytopenia in type 2B von Willebrand disease. Once weekly subcutaneous injections of rondoraptivon pegol may in the future be used for prophylaxis or treatment of VWD.

Keywords: aptamer rondoraptivon; pegol; vwf fviii; von willebrand; rondoraptivon pegol; type von

Journal Title: Blood Advances
Year Published: 2022

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