Photo by refargotohp from unsplash
Key Points • EVI1 exerts distinct roles in AML, including resistance, pathogenicity of aggressive diseases independent of stemness, and immune evasion.• ERG and cyclin D1 are leukemia-specific targets of EVI1,… Click to show full abstract
Key Points • EVI1 exerts distinct roles in AML, including resistance, pathogenicity of aggressive diseases independent of stemness, and immune evasion.• ERG and cyclin D1 are leukemia-specific targets of EVI1, providing potential therapeutic vulnerability of EVI1-associated AML.
Keywords:
roles aml;
erg cyclin;
evi1 exerts;
exerts distinct;
distinct roles
Journal Title: Blood Advances
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!
Journal Title: Blood Advances
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!