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Targets of autoantibodies in acquired hemophilia A are not restricted to factor VIII: data from the GTH-AH 01/2010 study

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Key Points • Seventy-eight percent of patients with AHA were found to have autoantibodies against targets other than factor VIII.• The data suggest that a generalized breakdown of self-tolerance mechanisms… Click to show full abstract

Key Points • Seventy-eight percent of patients with AHA were found to have autoantibodies against targets other than factor VIII.• The data suggest that a generalized breakdown of self-tolerance mechanisms is involved in the pathology of AHA.

Keywords: autoantibodies acquired; targets autoantibodies; hemophilia restricted; factor viii; viii data; acquired hemophilia

Journal Title: Blood Advances
Year Published: 2022

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