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Dynamin-2 deficiency causes age- and sex-dependent neutropenia and myelodysplasia in mice

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Key Points • Dynamin-2 haplodeficient female mice develop neutropenia with aging.• Neutropenia is because of defective production from dysmyelopoiesis and migration defects. Click to show full abstract

Key Points • Dynamin-2 haplodeficient female mice develop neutropenia with aging.• Neutropenia is because of defective production from dysmyelopoiesis and migration defects.

Keywords: sex dependent; causes age; age sex; mice; dynamin deficiency; deficiency causes

Journal Title: Blood Advances
Year Published: 2022

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