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Integrated transcriptome and trajectory analysis of cutaneous T-cell lymphoma identifies putative precancer populations

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Key Points • Integrated transcriptome analyses identify putative precancerous circulating clonal CD4+ T-cell populations in patients with CTCL.• The study results reveal promising therapeutic strategies via targeting of CD82 and… Click to show full abstract

Key Points • Integrated transcriptome analyses identify putative precancerous circulating clonal CD4+ T-cell populations in patients with CTCL.• The study results reveal promising therapeutic strategies via targeting of CD82 and JAK kinases.

Keywords: cell; transcriptome trajectory; integrated transcriptome; trajectory analysis; analysis cutaneous; cutaneous cell

Journal Title: Blood Advances
Year Published: 2022

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