Photo by matmacq from unsplash
Key Points • MADD-deficient cytotoxic cells display defect of degranulation, most likely due to impaired activation of RAB27A.• Patients with MADD deficiency may have a predisposition to develop HLH. Click to show full abstract
Key Points • MADD-deficient cytotoxic cells display defect of degranulation, most likely due to impaired activation of RAB27A.• Patients with MADD deficiency may have a predisposition to develop HLH.
Keywords:
kinase activating;
death domain;
activating death;
domain deficiency;
map kinase;
deficiency
Journal Title: Blood Advances
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!
Journal Title: Blood Advances
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!