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GATA1 controls numbers of hematopoietic progenitors and their response to autoimmune neuroinflammation

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Key Points • ΔdblGATA mice are resistant to EAE but not due to their lack of eosinophils.• GATA1 regulates numbers of HSPCs in the BM, and the ΔdblGATA mutation causes… Click to show full abstract

Key Points • ΔdblGATA mice are resistant to EAE but not due to their lack of eosinophils.• GATA1 regulates numbers of HSPCs in the BM, and the ΔdblGATA mutation causes a functional deficit during inflammation.

Keywords: numbers hematopoietic; gata1 controls; response autoimmune; controls numbers; hematopoietic progenitors; progenitors response

Journal Title: Blood Advances
Year Published: 2022

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