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Clinical outcomes associated with NPM1 mutations in patients with relapsed or refractory AML

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Key Points • In relapsed or refractory AML, mutated NPM1 has no impact on the risk of relapse or death.• The addition of venetoclax to salvage treatment for NPM1-mutated AML… Click to show full abstract

Key Points • In relapsed or refractory AML, mutated NPM1 has no impact on the risk of relapse or death.• The addition of venetoclax to salvage treatment for NPM1-mutated AML is associated with improved outcomes.

Keywords: refractory aml; clinical outcomes; associated npm1; npm1 mutations; outcomes associated; relapsed refractory

Journal Title: Blood Advances
Year Published: 2022

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