Key Points • Bending stress exerted on the plasma membrane by sickle hemoglobin polymerization enhances sulfatide-mediated adhesion of mature erythrocytes in SCD.• Inflammatory sphingomyelinase activity could result in abnormal adhesion… Click to show full abstract
Key Points • Bending stress exerted on the plasma membrane by sickle hemoglobin polymerization enhances sulfatide-mediated adhesion of mature erythrocytes in SCD.• Inflammatory sphingomyelinase activity could result in abnormal adhesion and membrane damage in sickle mature erythrocytes.
Keywords:
adhesion;
sphingomyelinase;
mature erythrocytes;
sickle mature
Journal Title: Blood Advances
Year Published: 2023
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Journal Title: Blood Advances
Year Published: 2023
Link to full text (if available)
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recommendations!