Photo by dlabokamisla from unsplash
Key Points • TIM-3/Gal-9 autocrine loop hijacks and constitutively activates canonical Wnt pathway in AML LSCs.• To hijack canonical Wnt pathway, HCK and p120-catenin, highly expressed on AML LSCs, play… Click to show full abstract
Key Points • TIM-3/Gal-9 autocrine loop hijacks and constitutively activates canonical Wnt pathway in AML LSCs.• To hijack canonical Wnt pathway, HCK and p120-catenin, highly expressed on AML LSCs, play crucial roles in signal transduction of TIM-3.
Keywords:
canonical wnt;
catenin;
wnt;
signaling hijacks;
tim signaling;
pathway
Journal Title: Blood Advances
Year Published: 2023
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!
Journal Title: Blood Advances
Year Published: 2023
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!