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Abatacept GVHD prophylaxis in unrelated hematopoietic cell transplantation for pediatric bone marrow failure

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Key Points • Four doses of Aba can be safely added to standard 2-drug GVHD prophylaxis in URD HCT for pediatric bone marrow failure.• No severe acute or chronic GVHD… Click to show full abstract

Key Points • Four doses of Aba can be safely added to standard 2-drug GVHD prophylaxis in URD HCT for pediatric bone marrow failure.• No severe acute or chronic GVHD was seen in pediatric patients with bone marrow failure with Aba-containing prophylaxis after URD HCT.

Keywords: bone marrow; marrow failure; pediatric bone; gvhd prophylaxis

Journal Title: Blood Advances
Year Published: 2023

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