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INR and vitamin K–dependent factor levels after vitamin K antagonist reversal with 4F-PCC or plasma

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Key Points • 4F-PCC rapidly restores vitamin K–dependent factors to hemostatic levels in patients treated with VKA immediately after infusion.• Postreversal INR may not accurately reflect vitamin K–dependent factor restoration… Click to show full abstract

Key Points • 4F-PCC rapidly restores vitamin K–dependent factors to hemostatic levels in patients treated with VKA immediately after infusion.• Postreversal INR may not accurately reflect vitamin K–dependent factor restoration after a 4F–PCC infusion.

Keywords: dependent factor; vitamin dependent; inr vitamin; factor levels; pcc

Journal Title: Blood Advances
Year Published: 2022

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