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SAMHD1 Single Nucleotide Polymorphisms Impact Outcome in Children with Newly Diagnosed Acute Myeloid Leukemia.

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Key Points • SNPs within SAMHD1 are predictive of clinical outcome in 3 independent cohorts of children diagnosed with AML.• Future in-depth functional evaluation and validation in larger cohorts are… Click to show full abstract

Key Points • SNPs within SAMHD1 are predictive of clinical outcome in 3 independent cohorts of children diagnosed with AML.• Future in-depth functional evaluation and validation in larger cohorts are needed to establish its prognostic relevance in AML treatment.

Keywords: outcome children; nucleotide polymorphisms; impact outcome; polymorphisms impact; single nucleotide; samhd1 single

Journal Title: Blood advances
Year Published: 2023

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