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Caplacizumab as frontline therapy in addition to standard treatment in iTTP

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We read with interest the meta-analysis performed by Djulbegovic et al about the use of caplacizumab as a treatment for patients with immune thrombotic thrombocytopenic purpura (iTTP). 1 We respectfully… Click to show full abstract

We read with interest the meta-analysis performed by Djulbegovic et al about the use of caplacizumab as a treatment for patients with immune thrombotic thrombocytopenic purpura (iTTP). 1 We respectfully disagree with some of the conclusions drawn by the authors. Firstly, the authors state that the addition of caplacizumab to the standard of care did not signi fi cantly reduce all-cause mortality compared with standard of care alone

Keywords: addition; ittp; caplacizumab frontline; standard; caplacizumab; treatment

Journal Title: Blood Advances
Year Published: 2022

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