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IgG testing, immunoglobulin replacement therapy, and infection outcomes in patients with CLL or NHL: real-world evidence

Key Points • Hypogammaglobulinemia, infections/severe infections, and antimicrobial use were decreased in patients with CLL or NHL treated with IgRT.• Increased IgG testing was associated with increased hypogammaglobulinemia detection and… Click to show full abstract

Key Points • Hypogammaglobulinemia, infections/severe infections, and antimicrobial use were decreased in patients with CLL or NHL treated with IgRT.• Increased IgG testing was associated with increased hypogammaglobulinemia detection and lower rates of severe infection.

Keywords: cll nhl; patients cll; testing immunoglobulin; igg testing; infection; immunoglobulin replacement

Journal Title: Blood Advances
Year Published: 2024

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