LAUSR

Introduction: Inspiratory muscle training (IMT)might be an efficient treatment modality for patients with weaning failure. A recently developed IMT device applies a tapered flow resistive load(TFRL)with visual breathing pattern feedback that might result in better training response than the typically used mechanical threshold loading(MTL) Aim: To investigate the difference in breathing pattern response during IMT using either MTL or TFRL in difficult to wean ICU patients. Methods: 6 patients (1female), age 46±16 years, BMI 23±6Kg/m 2 , MIP 41±19cmH 2 O performed IMT sessions at highest tolerable load using both devices. After 14±5 days of training, breathing parameters from one training session performed with both devices at the same absolute resistance were compared using paired T-test. Results: TFRL-IMT enabled patients to achieve higher inspiratory volume and larger work of breathing while resulting in less fatiguing contraction pattern than MTL-IMT(Table). Conclusions: It should be evaluated whether TFRL-IMT is better tolerated by these patients and if it will result in larger respiratory muscle function improvements than MTL-IMT.