Patients with advanced sarcoidosis may develop pulmonary hypertension for a variety of reasons [1]. One of the earlier papers noting the incidence and severity of this problem came from the… Click to show full abstract
Patients with advanced sarcoidosis may develop pulmonary hypertension for a variety of reasons [1]. One of the earlier papers noting the incidence and severity of this problem came from the clinic run by Gianfranco Rizzato in Milan [2]. Despite the well documented association noted in that article, there were very few reports of sarcoidosis-associated pulmonary hypertension (S-APH) until 20 years later. Over the past 10 years, reports regarding S-APH have come from the USA [3–5], Europe [1, 6, 7] and Japan [8]. These studies found that S-APH was most frequently seen patients with fibrotic disease and was associated with increased mortality [9, 10]. More evidence that sarcoidosis patients with pulmonary hypertension respond to therapy http://ow.ly/H40c30fetN4
               
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