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In this review article we present the evidence to date supporting the role of the calcium-sensing receptor (CaSR) as a key, pluripotential molecular trigger for asthma and speculate on the… Click to show full abstract
In this review article we present the evidence to date supporting the role of the calcium-sensing receptor (CaSR) as a key, pluripotential molecular trigger for asthma and speculate on the likely benefits of topical therapy of asthma with negative allosteric modulators of the CaSR: calcilytics. Negative allosteric modulators of the calcium-sensing receptor (calcilytics) delivered topically to the airways have the potential to revolutionise asthma therapy https://bit.ly/3tdSZkC
Keywords:
calcium sensing;
therapy;
allosteric modulators;
sensing receptor;
negative allosteric
Journal Title: European Respiratory Journal
Year Published: 2022
Link to full text (if available)
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Journal Title: European Respiratory Journal
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!