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When present during the course of COPD, pulmonary hypertension (PH) is usually of moderate severity: the mean pulmonary artery pressure (mPAP) at rest ranges from 25 to 35 mmHg, with preserved… Click to show full abstract
When present during the course of COPD, pulmonary hypertension (PH) is usually of moderate severity: the mean pulmonary artery pressure (mPAP) at rest ranges from 25 to 35 mmHg, with preserved cardiac output [1, 2]. However, a subset of COPD patients presents a particular vascular phenotype called severe PH, characterised by a much higher mPAP or a low cardiac index [1–8]. According to the latest world symposium on PH, severe PH-COPD is defined as mPAP ≥35 mmHg or mPAP ≥25 mmHg with low cardiac index (<2 L·min−1·m−2) [1, 2]. This prospective study dealing with 99 incident patients followed over several years, without any patients lost to follow-up, confirms, with good-quality data, that the prognosis associated with severe PH-COPD is very poor https://bit.ly/3DHjYIm
Journal Title: European Respiratory Journal
Year Published: 2022
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