LAUSR

Domiciliary noninvasive ventilation (DNIV) use in stable hypercapnic COPD is becoming increasingly widespread.However, factors related to compliance remain to be defined. Aim: Assess the predictive factors related to compliance to domiciliary NIV in COPD patients and evaluate its impact on symptoms and hospitalization rate. Retrospective comparative study (2011- 2019) including stable hypercapnic COPD patients under DNIV for at least 1 year. Patients were divided in 2 groups: Group 1 (G1) « high-compliance » patients who used NIV regularly, night or daytime and ≥5 hours/d, and group (G2) « low-compliance » patients who used NIV irregularly and One hundred and forty patients with a mean age of 68±10.3 years were enrolled, of whom 86% were males. They were using DNIV for 2.3±2 years. the most common comorbidities were cardiac failure (67%) diabetes mellitus (65%),and obesity (52%). About 89.4% were using domiciliary long-term oxygen therapy .Of the patients, 87.4% were using the device in spontaneous time (ST) mode,12.6% in spontaneous (S) mode . Mean inspiratory positive airway pressure (IPAP) used was 18±5.5 cmH2O, and mean expiratory positive airway pressure was 5.8±1.3 cmH2O. ST mode was more frequent in G1 (56 % vs 74% p Accurate determination of the patients who have better compliance to NIV will enable better patient selection and also help in defining optimal ventilator