LAUSR

Introduction: ChILD represent a heterogeneous group of rare and mostly severe disorders. In France, around 400 patients with chILD are listed. In adults, multidisciplinary teams (MDT) meetings are recognized as a crucial tool in such rare lung diseases. We aim at reporting the French experience of MDT meetings for chILD. Methods: On-line, video-conference MDT meetings have been held every month since 2018. For each patient, a standardized form is filled up by the clinician and sent to the Reference center for rare lung diseases (www.respiFIL.fr, www.respirare.fr). The MDT meetings include experts in the field with the aim of discussing diagnosis or treatment issues related to ChILD. After the MDT meeting, a report is established and sent to the requesting team. Results: In the last 20 months, 20 MDT were held and 107 patients were discussed. Participants were pediatric pulmonologists, geneticists, genetic counselor, pathologist, pediatric radiologists, and adult pulmonologists. The median age of the patients was 2 years-old. They were mainly followed in France but 14 (13%) patients were presented by international colleagues. The demands included a diagnosis issue (2%), management (19%), or both (75%). The MDT meetings allowed to precise or modify the ILD etiology in 1/3 of the patients; and to excluded ILD in 11 (10%). ILD remained of undefined cause for 19 (24%) vs 25 (32%). Conclusion: MDT meetings for chILD are easily feasible. They provide an important epidemiologic input by increasing the chILD case collection (+25%). They are an opportunity to collectively improve our knowledge on diagnosis and management of these rare diseases and to discuss genetic council issues.