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The STELVIO trial, a game changer for bronchoscopic lung volume reduction in patients with severe emphysema

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Chronic obstructive pulmonary disease (COPD) is characterised by persistent respiratory symptoms and airflow limitation, which is caused by small airway disease (bronchiolitis) and alveolar destruction (emphysema) [1]. Patients primarily suffering… Click to show full abstract

Chronic obstructive pulmonary disease (COPD) is characterised by persistent respiratory symptoms and airflow limitation, which is caused by small airway disease (bronchiolitis) and alveolar destruction (emphysema) [1]. Patients primarily suffering from severe emphysema are often limited in exercise capacity due to the consequences of hyperinflation [2]. The STELVIO trial was crucial to ensure that bronchoscopic lung volume reduction using one-way valves has evolved from an experimental intervention into a state-of-the-art treatment option for specific patients with advanced emphysema http://bit.ly/2IgMrsp

Keywords: lung volume; bronchoscopic lung; stelvio trial; severe emphysema; volume reduction

Journal Title: Breathe
Year Published: 2020

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