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Is there clinical value in performing capsaicin cough challenges in patients with severe asthma?

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Over 330 million people have been diagnosed with asthma worldwide [1], of whom 5–10% are classified as severe [2]. Despite use of high doses of inhaled corticosteroids (ICS), long-acting bronchodilators… Click to show full abstract

Over 330 million people have been diagnosed with asthma worldwide [1], of whom 5–10% are classified as severe [2]. Despite use of high doses of inhaled corticosteroids (ICS), long-acting bronchodilators (LABA) and/or maintenance oral steroid use, patients with severe asthma account for over 50% of the asthma healthcare budget [3, 4]. Largely due to exacerbations requiring hospitalisation, and cost of treatments to control disease severity, the disease burden has serious implications for their health and quality of life [3–5]. Heightened capsaicin cough sensitivity is independently associated with poor asthma control in moderate-to-severe asthma patients https://bit.ly/3mkbLkI

Keywords: value performing; patients severe; capsaicin cough; clinical value; severe asthma; performing capsaicin

Journal Title: Breathe
Year Published: 2021

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