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High-dose glucocorticoid treatment of near-fatal bocavirus lung infection results in rapid recovery

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Human bocavirus (HBoV), which belongs to Parvoviridae, is a well-defined pathogen of respiratory infections, particularly in young children [1]. In contrast, the frequency of HBoV infections in adults with respiratory… Click to show full abstract

Human bocavirus (HBoV), which belongs to Parvoviridae, is a well-defined pathogen of respiratory infections, particularly in young children [1]. In contrast, the frequency of HBoV infections in adults with respiratory symptoms is virtually unknown and its causative role in respiratory failure is debated [1, 2]. Furthermore, the observation that dexamethasone is beneficial in COVID-19 patients with respiratory failure requiring respiratory support has gained great interest [3]. However, whether glucocorticoid treatment is useful in other severe viral respiratory diseases is a matter of controversy [4]. Human bocavirus (HBoV) has to be considered a life-threatening pathogen in adults with atypical pneumonia. Pulsed high-dose glucocorticoid treatment may be beneficial in patients suffering from severe pulmonary disease caused by HBoV or other viruses. https://bit.ly/3epiMyO

Keywords: high dose; glucocorticoid treatment; bocavirus; treatment near; dose glucocorticoid

Journal Title: ERJ Open Research
Year Published: 2021

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